1.in charge of A管理，负责照料，
含义是管理、负责、照料的对象是A
He's in charge of the hospital.
他主持医院工作。
He will be in charge of all hiring and firing at PHA.
他将负责公共房产管理局所有人员的雇用和解聘事务。
She implied that she was the one in charge of the whole project.
她暗示她是整个计划的负责人。
He is in charge of the school work.
他负责学校工作。
Det Supt Bassett was in charge of the murder enquiry.
探长巴西特负责调查该谋杀案。
She demanded to know who was in charge of this action.
她要求知道谁负责这次行动。
He is in charge of the general affairs.
他管总务。
He is in charge of the task.
这项工作归他管。
You are in charge of the job. How could you evade the issue?
你是负责人，你怎么能对这个问题不置可否？
The Drafting Committee will be in charge of working out a draft resolution to be submitted to the Conference for deliberation.
起草委员会将负责起草提交大会讨论的决议草案。
He is in charge of the civilian side of the UN mission
他在联合国使团中负责平民方面的事务。
He was the officer in charge of operations.
他是负责指挥作战行动的军官。
If his reactions are so slow, he shouldn't be in charge of a bus
如果他的反应太慢，就不应该开公交汽车。
2.in the charge of A由……照料
含义是由A来管理、负责、照料……
The work in the charge of our monitor has been finished.
由我们班长负责的这项工作已经做完了。
I am in the charge of them two.
我受他们两人领导。
Our class is in the charge of her.
我们班由她负责。
The factory was in the charge of Mr. White.
怀特先生负责管理这个工厂。
This department is in the charge of Sun Qing.
这一部门由孙清主管。
The children were in the charge of Miss Taylor.
孩子们由泰勒小姐照顾。
试比较：
The nurse was left in charge of the children.
保姆留下来照料孩子们。
The children were left in the charge of a neighbor.
孩子们留下来由一位邻居照料。
记忆口诀：没有the的自然是没有资格去负责照顾别人的；有the的自然是有资格去负责照顾别人的。